General (applicable in most programs)
CTRL + C: Copy
CTRL + X: Cut
CTRL + V: Paste
CTRL + Z: Undo
CTRL + A: Select all
CTRL + F4: Close the active document in programs that enable you to have multiple documents open simultaneously.
CTRL + ESC: Display the Start menu.
CTRL while dragging an item: Copy the selected item.
CTRL + SHIFT while dragging an item: Create a shortcut to the selected item.
CTRL + RIGHT ARROW: Move the insertion point to the beginning of the next word.
CTRL + LEFT ARROW: Move the insertion point to the beginning of the previous word.
CTRL + DOWN ARROW: Move the insertion point to the beginning of the next paragraph.
CTRL + UP ARROW: Move the insertion point to the beginning of the previous paragraph.
CTRL + SHIFT with any of the arrow keys: Highlight a block of text.
SHIFT when you insert a CD-ROM into the CD-ROM drive: Prevent the CD-ROM from automatically playing.
SHIFT with any of the arrow keys: Select more than one item in a window or on the desktop, or select text in a document.
SHIFT + DELETE: To delete the selected item permanently without placing it in the Recycle Bin.
SHIFT + F10: Display the shortcut menu for the selected item.
ALT + ENTER: View the properties for the selected item.
ALT + F4: Close the active item, or quit the active program.
ALT + ENTER: Display the properties of the selected object.
ALT + SPACEBAR: Open the shortcut menu for the active window.
ALT + TAB: Switch between the open items.
ALT + ESC: Cycle through items in the order that they had been opened.
ALT + SPACEBAR: Display the System menu for the active window.
ALT + Underlined letter in a menu name: Perform the corresponding command.
F2 key: Rename the selected item.
F3 key: Search for a file or a folder.
F4 key: Display the Address bar list in My Computer or Windows Explorer.
F5 key: Update the active window.
F6 key: Cycle through the screen elements in a window or on the desktop.
F10 key: Activate the menu bar in the active program.
RIGHT ARROW: Open the next menu to the right, or open a submenu.
LEFT ARROW: Open the next menu to the left, or close a submenu.
BACKSPACE: View the folder one level up in My Computer or Windows Explorer.
ESC: Cancel the current task.
CTRL + SHIFT + ESC: Open Task Manager.
Dialog box
CTRL + TAB: Move forward through the tabs.
CTRL + SHIFT + TAB: Move backward through the tabs.
SHIFT + TAB: Move backward through the options.
ALT + Underlined letter: Perform the corresponding command or select the corresponding option.
F1 key: Display Help.
F4 key: Display the items in the active list.
TAB: Move forward through the options.
ENTER: Perform the command for the active option or button.
SPACEBAR: Select or clear the check box if the active option is a check box.
Arrow keys: Select a button if the active option is a group of option buttons.
BACKSPACE: Open a folder one level up if a folder is selected in the Save As or Open dialog box
Microsoft natural shortcuts
Windows Logo: Display or hide the Start menu.
Windows Logo + D: Display the desktop.
Windows Logo + M: Minimize all of the windows.
Windows Logo + SHIFT + M: Restore the minimized windows.
Windows Logo + E: Open My Computer.
Windows Logo + F: Search for a file or a folder.
Windows Logo + R: Open the Run dialog box.
Windows Explorer
END: Display the bottom of the active window.
HOME: Display the top of the active window.
NUM LOCK + Asterisk sign (*): Display all of the subfolders that are under the selected folder.
NUM LOCK + Plus sign ( + ): Display the contents of the selected folder.
NUM LOCK + Minus sign (-): Collapse the selected folder.
LEFT ARROW: Collapse the current selection if it is expanded, or select the parent folder.
RIGHT ARROW: Display the current selection if it is collapsed, or select the first subfolder.
Microsoft Internet Explorer
F5: Refresh the current Web page.
CTRL + R: Refresh the current Web page.
CTRL + O: Open the Open dialog box.
CTRL + F: Start the Find utility.
CTRL + H: Open the History bar.
CTRL + I: Open the Favorites bar.
CTRL + B: Open the Organize Favorites dialog box.
CTRL + E: Open the Search bar.
CTRL + W: Close the current window.
CTRL + P: Open the Print dialog box.
CTRL + N: Start another instance of the browser with the same Web address